Ifi204 macrophage
WebWhile the role of IFI204 and IFI205 in macrophages has been previously studied,,, nothing was known about IFI207’s function, and we therefore focused on characterizing this PYHIN. To study IFI207 protein expression in macrophages, we generated and validated a rabbit anti-IFI207 peptide antibody ( Figure S1 L). Web18 jun. 2024 · In macrophages, IRF1 drives M1 polarization by increasing the expression of pro-inflammatory cytokines and chemokines . In addition, IRF1 + Mϕ displays a …
Ifi204 macrophage
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Web2 nov. 2016 · Inhibits the transcription of ribosomal RNA. May inhibit DNA binding by UBTF. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways. Acts as a coactivator of RUNX2 during osteogenesis. May be involved in macrophage differentiation. Web23 jul. 2024 · LY6E is a member of the LY6/uPAR family of glycosylphosphatidylinositol-anchored proteins, and is implicated in diverse cellular processes 15. To evaluate the specificity of LY6E for inhibiting...
Web15 jan. 2024 · Macrophages were also a major source of CXCL9 in MC38 tumors and analysis of an independent, previously generated single-cell RNA-seq dataset of tumor-infiltrating immune cells in the CT26 tumor model revealed that CXCL9 and CXCL10 were predominantly expressed by immune cells that also coexpressed the macrophage … Web18 mrt. 2024 · Here we show that IFI204 is required for host defense against the infection of Staphylococcus aureus, an extracellular bacterial pathogen. IFI204 deficiency results in …
Web20 feb. 2015 · To determine whether the reduced type I IFN response to F. novicida in cGAS KO macrophages was due to lower expression of the Ifi204 gene, we stably expressed Ifi204 in WT, cGAS KO, Ifi204 KO, and Sting KO RAW264.7 macrophages. Ectopic expression of Ifi204 led to increased Ifi204 mRNA expression in all cells (Fig. 4A). Web4 apr. 2024 · Ifi204 is a regulator of monocyte/macrophage differentiation and make possible a connection with other myeloid regulators [review] This gene product interacts …
Web2 jun. 2024 · Thrombospondin-1 (THBS1) is a matrix glycoprotein that can affect fibrosis by activating TGF- β 1, which plays a key role in wound repair and tissue regeneration; therefore, we investigated the effects of THBS1 on the biological function of hypertrophic scar fibroblasts. THBS1 expression was measured in hypertrophic scars and adjacent …
WebView Rabbit Polyclonal anti-Ifi204 Antibody (NBP2-27153). Validated Applications: WB, IHC, IHC-P. Validated Species: Mouse. Sample size available. Skip to main content ... It is also reported that Ifi204 is trancriptionally activated in response to M-CSF and thus involved in macrophage differentiation in myeloid progenitor cells. results of going silicone freeWeb20 feb. 2015 · We created cGAS, Ifi204, and Sting functional knockouts in RAW264.7 macrophages and demonstrated that cGAS and Ifi204 cooperate to sense dsDNA and activate the STING-dependent type I IFN pathway. results of gabriel fernandez trialWeb8 aug. 2024 · Macrophages play pivotal roles in the progression and regression of atherosclerosis. Accumulating evidence suggests that macrophage polarization into an anti-inflammatory M2 state is a key... prtiscore shooting vestWeb1 apr. 2015 · We created cGAS, Ifi204, and Sting functional knockouts in RAW264.7 macrophages and demonstrated that cGAS and Ifi204 cooperate to sense dsDNA and … results of georgia runoff 2022WebThe interferon-inducible gene, Ifi204, is transcriptionally activated in response to M-CSF, and its expression favors macrophage differentiation in myeloid progenitor … results of genesis golf 2023Web30 mei 2024 · Macrophage depletion enhances the efficacy of ruxolitinib in mammary tumor models. ( A) Kaplan–Meier curves of HC-11/R1 or 4T1-transplanted ( C) WT BALB/c mice treated with DMSO or Rux with Control ( n = 4–5 mice per group) or Clodronate liposomes ( n = 8–10 mice per group). prt is not found. it might have been wipedWebWe found that IFI204 was acetylated in macrophages during M. bovis infection and the acetylated protein was distributed in cytoplasm but not in the nucleus ( Figure 4B). We … prtion of network address