Web1 day ago · A risk model based on lipid metabolism-related genes may predict prognosis and immunotherapeutic response in colon cancer. CYP19A1-catalyzed estrogen biosynthesis promotes vascular abnormality and inhibits CD8+ T cell function through the upregulation of PD-L1, IL-6 and TGF-β via GPR30-AK … WebAug 1, 2024 · Abstract It is well accepted that Forkhead box protein L2 (Foxl2) and aromatase (Cyp19a1; the enzyme responsible for estrogen synthesis) are critical for …
Multi-tissue transcriptome-wide association study identifies eight
WebYulin mixture can decrease the level of miR-320 and increase the expression of SF-1 and Cyp19a1 in ovary, thereby regulating the ovarian granulosa cell proliferation and … WebOct 7, 2024 · A survey of the transcriptomic landscape of the mouse ovary at the single-cell level reveals both the cellular complexity of this organs and the dynamic nature of the cellular states that accompany estrous cycling. … hudi demo
JCI - The ovary: basic biology and clinical implications
WebJun 1, 2011 · In particular, the presence of CYP19A1 transcript and protein (the present study and Ref. 20) confirms that there is the potential for estradiol to have a role in local signaling in the fetal ovary, ... and genistein inhibit oocyte nest breakdown and primordial follicle assembly in the neonatal mouse ovary in vitro and in vivo. Endocrinology. 148: WebJul 1, 2009 · The human aromatase gene (CYP19A1) has eleven tissue-specific untranslated first exons, while only three have been described in the mouse Cyp19A1 … WebYulin mixture can decrease the level of miR-320 and increase the expression of SF-1 and Cyp19a1 in ovary, thereby regulating the ovarian granulosa cell proliferation and apoptosis. 摘要 本研究将多囊卵巢综合征 (PCOS)小鼠模型随机分为6组:空白对照组、克罗米芬组、PCOS组、Yulin合剂高/中/低剂量组。 给药5周后处死大鼠。 酶联免疫吸附法检测血 … hudi datahub