Cyclophosphamid kardiotoxizität
WebFeb 21, 2024 · Kanda Y, Matsumura T, Maki K, et al. Fatal cardiac toxicity in two patients receiving same-day administration of cyclophosphamide and cytarabine as conditioning for hematopoietic stem cell transplantation. Haematologica 2001; 86:1002. Ishida S, Doki N, Shingai N, et al. WebJan 14, 2009 · In accordance with the increasing number of different oncologic drugs, including monoclonal antibodies and tyrosine kinase inhibitors, chemotherapy-induced cardiotoxicity can present in various manifestations, such as cardiomyopathy, myocardial ischemia, pericarditis or arrhythmias.
Cyclophosphamid kardiotoxizität
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WebSep 4, 2024 · Pathogenesis of acute CYC toxicity is thought to be related to toxic endothelial damage leading to extravasation of active CYC metabolites and increased free oxygen radicals, with consequent... WebPentostatin, a purine analogue used in the treatment of hairy cell leukemia and other hematologic malignancies, may have several cardiotoxic effects, 66 including MI, CHF, and arrhythmias. 67 Cardiotoxicity is particularly prominent when pentostatin is given with high doses of cyclophosphamide in preparation for bone marrow transplantation. 68
WebAug 14, 2024 · The dose-limiting toxic effect of cyclophosphamide (CY) is cardiotoxicity. The pathogenesis of myocardial damage is poorly understood, and there is no established means of prevention. In previous studies, we suggested that for CY-induced cardiotoxicity, whereas acrolein is the key toxic metabolite, carboxyethylphosphoramide mustard … WebFeb 7, 2024 · The clinical features of fatal cyclophosphamide-induced cardiotoxicity in a conditioning regimen for allogeneic hematopoietic stem cell transplantation (allo-HSCT). Ann Hematol 2016; 95(7): 1145–1150. Crossref. PubMed. Google Scholar. 35. Duléry R, Mohty R, Labopin M, et al. Early cardiac toxicity associated with post-transplant ...
WebDec 19, 2024 · Cyclophosphamide is an alkylating agent that is used for a variety of malignancies, including breast cancer, lung cancer, lymphomas, and in conditioning regimens before stem cell transplantation. High-dose cyclophosphamide (>1.5 g/m 2 /day) is considered to be highly cardiotoxic, with CTRCD incidences ranging from 7% to 28% ( … WebJan 22, 2024 · Other chemotherapy drugs that may cause cardiac toxicity are: Cyclophosphamide (Cytoxan ®) Fluorouracil (5-FU) Mitoxantrone (Novantrone ®) Cancer drugs that have been reported to cause abnormalities in heart rate or rhythm in more than 10% of patients include: Arsenic trioxide (Trisenox ®) Daunorubicin (Cerubidine ®) …
Web시클로포스파미드 ( cyclophosphamide, CP, 다른 이름: cytophosphane 등) [1] 는 화학요법 으로서, 또 면역억제제 로서 사용되는 약물이다. [2] 화학 요법으로서 림프종, 다발성 골수종, 백혈병, 난소암, 유방암, 소세포폐암, 신경모세포종, 육종 을 치료하기 위해 사용된다. [2] 면역 억제제로서 신증후군, 다발성 맥관염 동반 육아종, 그리고 잇따르는 장기 이식 및 기타 …
WebMay 1, 1981 · Cardiotoxicity Associated With High-Dose Cyclophosphamide Therapy JAMA Internal Medicine JAMA Network Scheduled Maintenance Our websites may be … khathab sheeferWebApr 15, 2024 · In a retrospective analysis of 102 patients, et al. patient support program conducted between January 2011 and December 2012, 11 patients [1 woman; not all sexes stated] aged 38−62 years were described, who developed ejection fraction (EF) decreased or ventricular ectopic, manifested as cardiac toxicity, following the therapy with … khatha sony onlineWebSep 15, 2024 · Cyclophosphamide’s cardiotoxic mechanism is unknown but is believed to result in endothelial dysfunction and coronary artery vasospasms. This action typically … khathaza real nameWebJan 1, 2013 · Cyclophosphamide-Induced Cardiomyopathy: A Case Report, Review, and Recommendations for Management Cyclophosphamide-Induced Cardiomyopathy: A Case Report, Review, and Recommendations for Management J Investig Med High Impact Case Rep. 2013 Jan 1;1 (1):2324709613480346. doi: … khatha onlineWebCyclophosphamide is a widely used anticancer and immunosuppressive prodrug that unfortunately causes severe adverse effects, including cardiotoxicity. Although the exact cardiotoxic mechanisms are not completely understood, a link between cyclophosphamide's pharmacologically active metabolites, name … khat from africaWebCyclophosphamid wird zur Behandlung von Krebserkrankungen und zur Therapie von schweren Autoimmunerkrankungen genutzt. Cyclophosphamid ist ein Arzneistoff mit … khatha numberWebApr 15, 2024 · In a retrospective analysis of 102 patients, et al. patient support program conducted between January 2011 and December 2012, 11 patients [1 woman; not all … is linux or windows more secure